| rlistat.htm
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| Drug
Information for: orlistat |
Click the
Links below for more Information on Warnings, Side
Effects, Pharmacology, Lactation and Pregnancy.
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| orlistat |
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| Pronunciation:
OR lih stat Brand:
Xenical
| What
is the most important
information I should know
about orlistat? |
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• |
Orlistat
may decrease your body's
absorption of some
fat-soluble vitamins. To
ensure adequate nutrition,
your doctor may recommend
taking a multivitamin that
contains vitamins D, E, K,
and beta-carotene. Take
your vitamin supplement
once a day, at least 2
hours before or after a
dose of orlistat. |
 |
• |
Do
not take more of this
medication than has been
prescribed for you. Doses
greater than 120 mg three
times a day have not been
shown to provide any
additional weight-loss
benefit. |
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• |
Orlistat
blocks some of the fat
that you eat from being
absorbed by your body. |
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• |
Orlistat
is used in the management
of obesity including
weight loss and weight
maintenance when used with
a reduced-calorie diet. |
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• |
Orlistat
may also be used for
purposes other than those
listed in this medication
guide. |
| Who
should not take orlistat? |
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• |
Do
not take orlistat without
first talking to your
doctor if you have |
|
· |
a
chronic malabsorption
syndrome, or |
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• |
You
may not be able to take
orlistat if you have any
of the conditions listed
above. |
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• |
Before
taking orlistat, talk to
your doctor if you |
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· |
have
a history of kidney
stones, |
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· |
have
anorexia or bulimia, |
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· |
take
any other weight-loss
medicine, or |
|
· |
take
cyclosporine (Sandimmune,
Neoral). |
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• |
You
may not be able to take
orlistat, or you may
require a dosage
adjustment or special
monitoring during your
treatment if you have any
of the conditions listed
above. |
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• |
Orlistat
is in the FDA pregnancy
category B. This means
that it is not expected to
harm an unborn baby. Do
not take orlistat without
first talking to your
doctor if you are
pregnant. |
 |
• |
It
is not known whether
orlistat passes into
breast milk. Do not take
orlistat without first
talking to your doctor if
you are breast-feeding a
baby. |
| How
should I take orlistat? |
|
• |
Take
orlistat exactly as
directed by your doctor.
If you do not understand
these directions, ask your
pharmacist, nurse, or
doctor to explain them to
you. |
 |
• |
Take
each dose with a full
glass of water. |
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• |
Orlistat
is usually taken with each
main meal that contains
fat. Orlistat can be taken
during meals or up to one
hour after a meal. |
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• |
Each
time you take orlistat,
your meal should contain
no more than about 30% of
calories from fat. Evenly
divide your daily intake
of fat, carbohydrates, and
protein over three main
meals a day. Talk to your
doctor about following a
healthy eating plan. |
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• |
If
you miss a meal, or if you
have a meal without fat,
you can skip your dose of
orlistat for that meal
also. |
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• |
If
orlistat is taken with any
one meal that is very high
in fat, there is an
increased chance of
digestive side effects. |
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• |
Do
not take more of this
medication than has been
prescribed for you. Doses
greater than 120 mg three
times a day have not been
shown to provide an
additional weight-loss
benefit. |
|
• |
Orlistat
may decrease your body's
absorption of some
fat-soluble vitamins. To
ensure adequate nutrition,
your doctor may recommend
taking a multivitamin that
contains vitamins D, E, K,
and beta-carotene. Take
your vitamin supplement
once a day, at least 2
hours before or after a
dose of orlistat. |
 |
• |
Store
orlistat at room
temperature away from
moisture and heat. |
| What
happens if I miss a dose? |
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• |
Take
the missed dose up to one
hour after a meal. If more
than one hour has passed
since your last meal, skip
the dose you missed and
take only your next
regularly scheduled dose
as directed. Do not take a
double dose of this
medication. |
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• |
If
you miss a meal, or if you
have a meal without fat,
you can skip your dose of
orlistat for that meal
also. |
| What
happens if I overdose? |
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• |
Seek
emergency medical
attention. |
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• |
Symptoms
of an orlistat overdose
are not known. |
| What
should I avoid while
taking orlistat? |
|
• |
Orlistat
may decrease your body's
absorption of some
fat-soluble vitamins. To
ensure adequate nutrition,
your doctor may recommend
taking a multivitamin that
contains vitamins D, E, K,
and beta-carotene. Take
your vitamin supplement
once a day, at least 2
hours before or after a
dose of orlistat. |
|
• |
Each
time you take orlistat,
your meal should contain
no more than about 30% of
calories from fat. Evenly
divide your daily intake
of fat, carbohydrates, and
protein over three main
meals a day. Talk to your
doctor about following a
healthy eating plan. |
| What
are the possible side
effects of orlistat? |
|
• |
Stop
taking orlistat and seek
emergency medical
attention if you
experience a rare allergic
reaction including
shortness of breath;
closing of your throat;
swelling of your lips,
tongue, or face; or hives. |
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• |
Other,
less serious side effects
are more likely to occur.
Continue to take orlistat
and talk to your doctor if
you experience |
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· |
an
urgent need to go to the
bathroom, |
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an
increased number of bowel
movements, |
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· |
an
inability to control bowel
movements, or |
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· |
orange
or brown colored oil in
your stool. |
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• |
The
bowel changes listed above
are a natural effect of
blocking fat and indicate
that orlistat is working.
They generally occur early
in treatment, particularly
after meals containing
higher amounts of fat than
are recommended. These
symptoms are usually
temporary and lessen or
disappear as you continue
treatment and keep to your
recommended diet of meals
containing 30% fat. |
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• |
Side
effects other than those
listed here may also
occur. Talk to your doctor
about any side effect that
seems unusual or that is
especially bothersome. |
| What
other drugs will affect
orlistat? |
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• |
Do
not take orlistat without
first talking to your
doctor if you are taking
any of the following
medicines: |
|
· |
cyclosporine
(Neoral, Sandimmune), or |
|
• |
You
may not be able to take
orlistat, or you may
require a dosage
adjustment or special
monitoring during your
treatment if you are
taking any of the
medicines listed above. |
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• |
Before
taking orlistat, tell your
doctor if you are taking
any of the following
medicines to lower
cholesterol: |
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· |
atorvastatin
(Lipitor), |
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· |
pravastatin
(Pravachol), or |
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• |
You
may require a dosage
adjustment or special
monitoring during
treatment if you are
taking any of the
cholesterol-lowering
medicines listed above. |
|
• |
Orlistat
may decrease your body's
absorption of some
fat-soluble vitamins. To
ensure adequate nutrition,
your doctor may recommend
taking a multivitamin that
contains vitamins D, E, K,
and beta-carotene. Take
your vitamin supplement
once a day, at least 2
hours before or after a
dose of orlistat. |
|
• |
Drugs
other than those listed
here may also interact
with orlistat. Talk to
your doctor and pharmacist
before taking or using any
other prescription or
over-the-counter
medicines. |
| Where
can I get more
information? |
|
• |
Your
pharmacist has more
information about orlistat
written for health
professionals that you may
read. |
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Remember,
keep this and all other medicines
out of the reach of children,
never share your medicines with
others, and use this medication
only for the indication
prescribed.
The
information in this leaflet is not
intended to cover all possible
uses, directions, precautions,
drug interactions, or adverse
effects. If you have questions
about the drugs you are taking,
check with your doctor, nurse, or
pharmacist.
© Multum Information Services
1999. Version: 2.010. Revision
date: 7/28/99. |
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Every effort has been made to ensure
that the information provided by Multum is
accurate, up-to-date, and complete, but no
guarantee is made to that effect. In
addition, the drug information contained
herein may be time sensitive and should
not be utilized as a reference resource
beyond the date hereof.
Multum's drug information does not
endorse drugs, diagnose patients, or
recommend therapy. Multum's drug
information is a reference resource
designed as supplement to, and not a
substitute for, the expertise, skill ,
knowledge, and judgement of healthcare
practitioners in patient care. The absence
of a warning for a given drug or drug
combination in no way should be construed
to indicate that the drug of drug
combination is safe, effective, or
appropriate for any given patient.
Multum Information Services, Inc. does
not assume any responsibility for any
aspect of healthcare administered with the
aid of information Multum provides.
Copyright 2000 Multum Information
Services, Inc. The information in
contained herein is not intended to cover
all possible uses, directions,
precautions, warnings, drug interactions,
allergic reactions, or adverse effects. If
you have questions about the drugs you are
taking, check with your doctor, nurse, or
pharmacist.
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