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| Drug
Information for: phendimetrazine |
Click the
Links below for more Information on Warnings, Side
Effects, Pharmacology, Lactation and Pregnancy.
|
| Leaflet
| Warnings | Side
Effects |
| Pharmacology
| Lactation |
Pregnancy |
| phendimetrazine |
|
|
|
| Pronunciation:
fen di MEH tra
zeen Brand:
Adipost, Anorex-SR,
Appecon, Bontril PDM, Bontril
Slow-Release, Melfiat, Obezine,
Phendiet, Plegine, Prelu-2,
Statobex
| What
is the most important
information I should know
about phendimetrazine? |
 |
• |
Use
caution when driving,
operating machinery, or
performing other hazardous
activities.
Phendimetrazine may cause
dizziness, blurred vision,
or restlessness, and it
may hide the symptoms of
extreme tiredness. If you
experience these effects,
avoid hazardous
activities. |
 |
• |
Phendimetrazine
is habit forming. You can
become physically and
psychologically dependent
on this medication, and
withdrawal effects may
occur if you stop taking
it suddenly after several
weeks of continuous use.
Talk to your doctor about
stopping this medication
gradually. |
 |
• |
Do
not crush, chew, or open
any "once-daily"
phendimetrazine tablets or
capsules. Swallow them
whole. |
|
• |
Phendimetrazine
is a sympathomimetic
amine, which is similar to
an amphetamine. It is also
known as an
"anorectic" or
"anorexigenic"
drug. Phendimetrazine
stimulates the central
nervous system (nerves and
brain), which increases
your heart rate and blood
pressure and decreases
your appetite. |
|
• |
Phendimetrazine
is used as a short-term
supplement to diet and
exercise in the treatment
of obesity. |
|
• |
Phendimetrazine
may also be used for
purposes other than those
listed in this medication
guide. |
| Who
should not take
phendimetrazine? |
 |
• |
You
cannot take
phendimetrazine if you |
|
· |
have
heart disease or high
blood pressure; |
|
· |
have
arteriosclerosis
(hardening of the
arteries); |
|
· |
have
taken a monoamine oxidase
inhibitor (MAOI) such as
isocarboxazid (Marplan),
tranylcypromine (Parnate),
or phenelzine (Nardil) in
the last 14 days; or |
|
· |
have
a history of drug or
alcohol abuse. |
|
• |
Before
taking this medication,
tell your doctor if you
have |
|
· |
problems
with your thyroid, |
|
· |
epilepsy
or another seizure
disorder, or |
|
• |
You
may not be able to take
phendimetrazine, or you
may require a lower dose
or special monitoring
during treatment if you
have any of the conditions
listed above. |
 |
• |
It
is not known whether
phendimetrazine will harm
an unborn baby. Do not
take phendimetrazine
without first talking to
your doctor if you are
pregnant. |
 |
• |
It
is also not known whether
phendimetrazine passes
into breast milk. Do not
take phendimetrazine
without first talking to
your doctor if you are
breast-feeding a baby. |
| How
should I take
phendimetrazine? |
|
• |
Take
phendimetrazine exactly as
directed by your doctor.
If you do not understand
these directions, ask your
pharmacist, nurse, or
doctor to explain them to
you. |
 |
• |
Take
each dose with a full
glass of water. |
 |
• |
Phendimetrazine
is usually taken once a
day (sustained release
formula) or two to three
times daily
(immediate-release
formula) before meals on
an empty stomach. |
|
• |
Do
not take phendimetrazine
in the evening because it
may cause insomnia. |
|
• |
Do
not crush, chew, or open
any "once-daily"
phendimetrazine tablets or
capsules. Swallow them
whole. |
|
• |
Never
take more of this
medication than is
prescribed for you. Too
much phendimetrazine could
be very dangerous to your
health. |
 |
• |
Store
phendimetrazine at room
temperature away from
moisture and heat. |
| What
happens if I miss a dose? |
|
• |
Take
the missed dose as soon as
you remember. However, if
it is almost time for your
next dose or if it is
already evening, skip the
missed dose and take only
your next regularly
scheduled dose. A dose
taken too late in the day
will cause insomnia. Do
not take a double dose
of this medication. |
| What
happens if I overdose? |
 |
• |
Seek
emergency medical
attention. |
|
• |
Symptoms
of a phendimetrazine
overdose include
restlessness, tremor,
rapid breathing,
confusion, hallucinations,
panic, aggressiveness,
nausea, vomiting,
diarrhea, an irregular
heartbeat, and seizures. |
| What
should I avoid while
taking phendimetrazine? |
|
• |
Use
caution when driving,
operating machinery, or
performing other hazardous
activities.
Phendimetrazine may cause
dizziness, blurred vision,
or restlessness, and it
may hide the symptoms of
extreme tiredness. If you
experience these effects,
avoid hazardous
activities. |
|
• |
Do
not take phendimetrazine
late in the day. A dose
taken too late in the day
can cause insomnia. |
| What
are the possible side
effects of phendimetrazine? |
|
• |
If
you experience any of the
following serious side
effects, stop taking
phendimetrazine and seek
emergency medical
attention: |
|
· |
an
allergic reaction
(difficulty breathing;
closing of your throat;
swelling of your lips,
tongue, or face; or
hives); |
|
· |
an
irregular heartbeat or
very high blood pressure
(severe headache, blurred
vision); or |
|
· |
hallucinations,
abnormal behavior, or
confusion. |
|
• |
Other,
less serious side effects
may be more likely to
occur. Continue to take
phendimetrazine and talk
to your doctor if you
experience |
|
· |
restlessness
or tremor, |
|
· |
nervousness
or anxiety, |
|
· |
dry
mouth or an unpleasant
taste in your mouth, |
|
· |
diarrhea
or constipation, or |
|
· |
impotence
or changes in your sex
drive. |
|
• |
Phendimetrazine
is habit forming. You can
become physically and
psychologically dependent
on this medication, and
withdrawal effects may
occur if you stop taking
it suddenly after several
weeks of continuous use.
Talk to your doctor about
stopping this medication
gradually. |
|
• |
Side
effects other than those
listed here may also
occur. Talk to your doctor
about any side effect that
seems unusual or that is
especially bothersome. |
| What
other drugs will affect
phendimetrazine? |
|
• |
You
cannot take
phendimetrazine if you
have taken a monoamine
oxidase inhibitor (MAOI)
such as isocarboxazid (Marplan),
tranylcypromine (Parnate),
or phenelzine (Nardil) in
the last 14 days. |
|
• |
Changes
in insulin and other
diabetes drug therapies
may be necessary during
treatment with
phendimetrazine. |
|
• |
Phendimetrazine
may reduce the effects of
guanethidine (Ismelin).
This could lead to an
increase in blood
pressure. Tell your doctor
if you are taking
guanethidine. |
|
• |
Before
taking this medication,
tell your doctor if you
are taking a tricyclic
antidepressant such as
amitriptyline (Elavil),
amoxapine (Asendin),
doxepin (Sinequan),
nortriptyline (Pamelor),
imipramine (Tofranil),
clomipramine (Anafranil),
protriptyline (Vivactil),
or desipramine (Norpramin).
These drugs may decrease
the effects of
phendimetrazine. |
|
• |
Drugs
other than those listed
here may also interact
with phendimetrazine. Talk
to your doctor and
pharmacist before taking
any prescription or
over-the-counter
medicines. |
| Where
can I get more
information? |
|
• |
Your
pharmacist has more
information about
phendimetrazine written
for health professionals
that you may read. |
|
Remember,
keep this and all other medicines
out of the reach of children,
never share your medicines with
others, and use this medication
only for the indication
prescribed.
The
information in this leaflet is not
intended to cover all possible
uses, directions, precautions,
drug interactions, or adverse
effects. If you have questions
about the drugs you are taking,
check with your doctor, nurse, or
pharmacist.
© Multum Information Services
1999. Version: 3.010. Revision
date: 4/15/99. |
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Every effort has been made to ensure
that the information provided by Multum is
accurate, up-to-date, and complete, but no
guarantee is made to that effect. In
addition, the drug information contained
herein may be time sensitive and should
not be utilized as a reference resource
beyond the date hereof.
Multum's drug information does not
endorse drugs, diagnose patients, or
recommend therapy. Multum's drug
information is a reference resource
designed as supplement to, and not a
substitute for, the expertise, skill ,
knowledge, and judgement of healthcare
practitioners in patient care. The absence
of a warning for a given drug or drug
combination in no way should be construed
to indicate that the drug of drug
combination is safe, effective, or
appropriate for any given patient.
Multum Information Services, Inc. does
not assume any responsibility for any
aspect of healthcare administered with the
aid of information Multum provides.
Copyright 2000 Multum Information
Services, Inc. The information in
contained herein is not intended to cover
all possible uses, directions,
precautions, warnings, drug interactions,
allergic reactions, or adverse effects. If
you have questions about the drugs you are
taking, check with your doctor, nurse, or
pharmacist.
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