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Sibutramine

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  Drug Information for:  

 sibutramine


Click the Links below for more Information on Warnings, Side Effects, Pharmacology, Lactation and Pregnancy.
 
Leaflet | Warnings | Side Effects
Pharmacology | Lactation | Pregnancy
sibutramine
Pronunciation: sih BYOO tra meen Brand: Meridia
What is the most important information I should know about sibutramine?
Do not take any other prescription or over-the-counter medicines without first talking to your doctor, especially weight-loss products, decongestants, antidepressants, cough suppressants, lithium, and migraine medicines.
It is very important to have your blood pressure and pulse monitored regularly while you are taking sibutramine.
Use caution when driving, operating machinery, or performing other hazardous activities. Sibutramine may cause dizziness, difficulty concentrating, or restlessness. If you experience these effects, avoid hazardous activities.
What is sibutramine?
Sibutramine affects chemicals in your body that are related to weight maintenance.
Sibutramine is used as a short-term supplement to diet and exercise in the treatment of obesity.
Sibutramine may also be used for purposes other than those listed in this medication guide.
Who should not take sibutramine?
You cannot take sibutramine if you
     · have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), tranylcypromine (Parnate), or phenelzine (Nardil) in the last 14 days;
     · have anorexia nervosa; or
     · are taking other weight-loss medicines.
Before taking this medication, tell your doctor if you have
     · high blood pressure;
     · heart disease, irregular heartbeats, congestive heart failure, or a history of stroke;
     · epilepsy or another seizure disorder;
     · gallstones;
     · glaucoma; or
     · liver disease.
You may not be able to take sibutramine, or you may require a lower dose or special monitoring if you have any of the conditions listed above.
Sibutramine is in the FDA pregnancy category C. This means that it is not known whether sibutramine will harm an unborn baby. Do not take sibutramine without first talking to your doctor if you are pregnant.
It is not known whether sibutramine passes into breast milk. Do not take sibutramine without first talking to your doctor if you are breast-feeding a baby.
How should I take sibutramine?
Take sibutramine exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.
Take each dose with a full glass of water.
Sibutramine is usually taken once a day. Follow your doctor's instructions.
Sibutramine can be taken with or without food.
Never take more of this medication than is prescribed for you. Too much sibutramine could be very dangerous to your health.
Store sibutramine at room temperature away from moisture and heat.
What happens if I miss a dose?
Take the missed dose as soon as you remember. However, if it is almost time for your next dose or if it is already evening, skip the missed dose and take only your next regularly scheduled dose. A dose taken too late in the day will cause insomnia. Do not take a double dose of this medication.
What happens if I overdose?
Seek emergency medical attention.
Symptoms of a sibutramine overdose are not known.
What should I avoid while taking sibutramine?
Use caution when driving, operating machinery, or performing other hazardous activities. Sibutramine may cause dizziness, difficulty concentrating, or restlessness. If you experience these effects, avoid hazardous activities.
What are the possible side effects of sibutramine?
If you experience any of the following serious side effects, stop taking sibutramine and seek emergency medical attention:
     · an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
     · an irregular heartbeat;
     · very high blood pressure (severe headache, blurred vision); or
     · seizures.
Other, less serious side effects may be more likely to occur. Continue to take sibutramine and talk to your doctor if you experience
     · restlessness or tremor,
     · nervousness or anxiety,
     · headache or dizziness,
     · insomnia,
     · dry mouth or an unpleasant taste in your mouth, or
     · constipation.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
What other drugs will affect sibutramine?
You cannot take sibutramine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), tranylcypromine (Parnate), or phenelzine (Nardil) in the last 14 days.
Before taking this medication, tell your doctor if you are taking
     · lithium (Lithobid, Eskalith, Lithonate, others),
     · sumatriptan (Imitrex),
     · dihydroergotamine (D.H.E.),
     · dextromethorphan (in many cough medicines),
     · meperidine (Demerol),
     · fentanyl (Duragesic),
     · pentazocine (Talacen, Talwin),
     · fluoxetine (Prozac),
     · sertraline (Zoloft),
     · paroxetine (Paxil),
     · fluvoxamine (Luvox), or
     · venlafaxine (Effexor).
Sibutramine may interact with the medicines listed above and cause anxiety, restlessness, loss of consciousness, confusion, weakness, tremor, poor coordination, fever, shivering, sweating, vomiting, a fast heartbeat, and other symptoms. These reactions can be very dangerous and require medical attention. Do not take any other prescription or over-the-counter medicines without first talking to your doctor, especially weight-loss products, decongestants, antidepressants, cough suppressants, lithium, or migraine medicines.
Drugs other than those listed here may also interact with sibutramine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.
Where can I get more information?
Your pharmacist has more information about sibutramine written for health professionals that you may read.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

The information in this leaflet is not intended to cover all possible uses, directions, precautions, drug interactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.
© Multum Information Services 1998. Version: 1.010. Revision date: 12/10/98.

Every effort has been made to ensure that the information provided by Multum is accurate, up-to-date, and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof.

Multum's drug information does not endorse drugs, diagnose patients, or recommend therapy. Multum's drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug of drug combination is safe, effective, or appropriate for any given patient.

Multum Information Services, Inc. does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides.

Copyright 2000 Multum Information Services, Inc. The information in contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.


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